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Synthesis of alkyl hydrogen (1-aminoalkyl)phosphonates

Radii Mikhailovich Khomutov 1
Radii Mikhailovich Khomutov
Elena Nikolaevich Khurs 1
Elena Nikolaevich Khurs
Tat'yana Ivanovna Osipova 1
Tat'yana Ivanovna Osipova
Published 2011-03-10
CommunicationVolume 21, Issue 2, 106-107
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Khomutov R. M., Khurs E. N., Osipova T. I. Synthesis of alkyl hydrogen (1-aminoalkyl)phosphonates // Mendeleev Communications. 2011. Vol. 21. No. 2. pp. 106-107.
GOST all authors (up to 50) Copy
Khomutov R. M., Khurs E. N., Osipova T. I. Synthesis of alkyl hydrogen (1-aminoalkyl)phosphonates // Mendeleev Communications. 2011. Vol. 21. No. 2. pp. 106-107.
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TY - JOUR
DO - 10.1016/j.mencom.2011.03.017
UR - https://mendcomm.colab.ws/publications/10.1016/j.mencom.2011.03.017
TI - Synthesis of alkyl hydrogen (1-aminoalkyl)phosphonates
T2 - Mendeleev Communications
AU - Khomutov, Radii Mikhailovich
AU - Khurs, Elena Nikolaevich
AU - Osipova, Tat'yana Ivanovna
PY - 2011
DA - 2011/03/10
PB - Mendeleev Communications
SP - 106-107
IS - 2
VL - 21
ER -
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@article{2011_Khomutov,
author = {Radii Mikhailovich Khomutov and Elena Nikolaevich Khurs and Tat'yana Ivanovna Osipova},
title = {Synthesis of alkyl hydrogen (1-aminoalkyl)phosphonates},
journal = {Mendeleev Communications},
year = {2011},
volume = {21},
publisher = {Mendeleev Communications},
month = {Mar},
url = {https://mendcomm.colab.ws/publications/10.1016/j.mencom.2011.03.017},
number = {2},
pages = {106--107},
doi = {10.1016/j.mencom.2011.03.017}
}
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Khomutov, Radii Mikhailovich, et al. “Synthesis of alkyl hydrogen (1-aminoalkyl)phosphonates.” Mendeleev Communications, vol. 21, no. 2, Mar. 2011, pp. 106-107. https://mendcomm.colab.ws/publications/10.1016/j.mencom.2011.03.017.

Abstract

Addition of hypophosphorous acid to aldoximes affords (1-aminoalkyl)phosphinic acids which on treatment with bromine in alkanols are transformed into alkyl hydrogen (1-aminoalkyl)phosphonates.

References

1.
Phosphorus amino acid analogs as inhibitors of leucine aminopeptidase
Giannousis P.P., Bartlett P.A.
Journal of Medicinal Chemistry, 1987
2.
Synthesis of phosphonic monoesters from phosphonous acids
3.
Khomutov R.M., Osipova T.I., Khurs E.N., Dzhavakhiya V.G.
Mendeleev Communications, 2008
4.
E. K. Baylis and W. Pickles, Eur. Pat. Appl. 2,039 (C1.C07F9/48), 1979.(Chem. Abstr., 1980, 92, 181668s).
7.
Multiple solid phase synthesis of (RS)-1-aminophosphinic acids
Boyd E.A., Chan W.C., Loh V.M.
Tetrahedron Letters, 1996
8.
1-Aminoalkylphosphonous acids. Part 1. Isosteres of the protein amino acids
Baylis E.K., Campbell C.D., Dingwall J.G.
Journal of the Chemical Society Perkin Transactions 1, 1984
9.
10.1016/j.mencom.2011.03.017_bib0045
Khomutov
Izv. Akad. Nauk SSSR, Ser. Khim., 1978
10.
10.1016/j.mencom.2011.03.017_bib0050
Kruglyak
Zh. Org. Khim., 1968
11.
10.1016/j.mencom.2011.03.017_bib0055
Kruglyak
Zh. Org. Khim., 1969