Abstract
A conjugate of folic acid with a hydrophobic polyethylene glycol derivative has been synthesised; the characteristics of the resulting sterically-stabilised system based on lipodipeptides for directed delivery of doxorubicine have been determined.
References
1.
Heyes J., Hall K., Tailor V., Lenz R., MacLachlan I.
Journal of Controlled Release,
2006
2.
Saul J.M., Annapragada A., Natarajan J.V., Bellamkonda R.V.
Journal of Controlled Release,
2003
3.
Leamon C.P., Low P.S.
Drug Discovery Today,
2001
4.
Leamon C.P., Low P.S.
Proceedings of the National Academy of Sciences of the United States of America,
1991
5.
Lee E.
Journal of Controlled Release,
2003
6.
10.1016/j.mencom.2010.11.008_bib0030
Sebyakin
Bioorg. Khim.,
2006
7.
Kawaguchi E., Shimokawa K., Ishii F.
Colloids and Surfaces B: Biointerfaces,
2008
8.
Hossann M., Wiggenhorn M., Schwerdt A., Wachholz K., Teichert N., Eibl H., Issels R.D., Lindner L.H.
Biochimica et Biophysica Acta - Biomembranes,
2007