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New functionalized aminofurazans as potential antimitotic agents in the sea urchin embryo assay

Aleksei Borisovich Sheremetev 1
Aleksei Borisovich Sheremetev
, 
Dmitrii Evgenievich Dmitriev 1
Dmitrii Evgenievich Dmitriev
, 
Nataliya K Lagutina 1
Nataliya K Lagutina
, 
Mikhail Mikhailovich Raikhshtat 1
Mikhail Mikhailovich Raikhshtat
, 
Aleksander (Alex) S Kiselev 2
Aleksander (Alex) S Kiselev
, 
Marina Nikolaevna Semenova 3
Marina Nikolaevna Semenova
, 
Natalie N Ikizalp 4
Natalie N Ikizalp
, 
Victor Vladimirovich Semenov 1, 4
Victor Vladimirovich Semenov
10.1016/j.mencom.2010.05.002
Published 2010-05-06
Communication , Volume 20, Issue 3, 132-134
13
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Sheremetev A. B. et al. New functionalized aminofurazans as potential antimitotic agents in the sea urchin embryo assay // Mendeleev Communications. 2010. Vol. 20. No. 3. pp. 132-134.
GOST all authors (up to 50) Copy
Sheremetev A. B., Dmitriev D. E., Lagutina N. K., Raikhshtat M. M., Kiselev A. (. S., Semenova M. N., Ikizalp N. N., Semenov V. V. New functionalized aminofurazans as potential antimitotic agents in the sea urchin embryo assay // Mendeleev Communications. 2010. Vol. 20. No. 3. pp. 132-134.
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TY - JOUR
DO - 10.1016/j.mencom.2010.05.002
UR - https://mendcomm.colab.ws/publications/10.1016/j.mencom.2010.05.002
TI - New functionalized aminofurazans as potential antimitotic agents in the sea urchin embryo assay
T2 - Mendeleev Communications
AU - Sheremetev, Aleksei Borisovich
AU - Dmitriev, Dmitrii Evgenievich
AU - Lagutina, Nataliya K
AU - Raikhshtat, Mikhail Mikhailovich
AU - Kiselev, Aleksander (Alex) S
AU - Semenova, Marina Nikolaevna
AU - Ikizalp, Natalie N
AU - Semenov, Victor Vladimirovich
PY - 2010
DA - 2010/05/06
PB - Mendeleev Communications
SP - 132-134
IS - 3
VL - 20
ER -
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@article{2010_Sheremetev,
author = {Aleksei Borisovich Sheremetev and Dmitrii Evgenievich Dmitriev and Nataliya K Lagutina and Mikhail Mikhailovich Raikhshtat and Aleksander (Alex) S Kiselev and Marina Nikolaevna Semenova and Natalie N Ikizalp and Victor Vladimirovich Semenov},
title = {New functionalized aminofurazans as potential antimitotic agents in the sea urchin embryo assay},
journal = {Mendeleev Communications},
year = {2010},
volume = {20},
publisher = {Mendeleev Communications},
month = {May},
url = {https://mendcomm.colab.ws/publications/10.1016/j.mencom.2010.05.002},
number = {3},
pages = {132--134},
doi = {10.1016/j.mencom.2010.05.002}
}
MLA
Cite this
MLA Copy
Sheremetev, Aleksei Borisovich, et al. “New functionalized aminofurazans as potential antimitotic agents in the sea urchin embryo assay.” Mendeleev Communications, vol. 20, no. 3, May. 2010, pp. 132-134. https://mendcomm.colab.ws/publications/10.1016/j.mencom.2010.05.002.

Abstract

A series of new furazan (1,2,5-oxadiazole) derivatives based on structural overlap with combretastatin have been synthesized. Targeted molecules were evaluated using the sea urchin embryo assay; several agents demonstrated 1–4μmol dm–3 antiproliferative activity in this in vivo model.

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