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Bromination of indomethacin

Alexandre Vasil'evich Ivachtchenko ^{1, 2}

Alexandre Vasil'evich Ivachtchenko

Pavel Mikhailovich Yamanushkin ¹

Pavel Mikhailovich Yamanushkin

Oleg Dmitrievich Mitkin ¹

Oleg Dmitrievich Mitkin

Oleg Ivanovich Kiselev ³

Oleg Ivanovich Kiselev

¹ Department of Organic Chemistry, Chemical Diversity Research Institute, Khimki, Moscow Region, Russian Federation

² ChemDiv Inc., San Diego, CA, USA

³ A.A. Smorodintsev Research Institute of Influenza, St. Petersburg, Russian Federation

10.1016/j.mencom.2010.03.016

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Published 2010-03-05

Communication , Volume 20, Issue 2, 111-112

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Supporting information

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Ivachtchenko A. V. et al. Bromination of indomethacin // Mendeleev Communications. 2010. Vol. 20. No. 2. pp. 111-112.

GOST all authors (up to 50) Copy

Ivachtchenko A. V., Yamanushkin P. M., Mitkin O. D., Kiselev O. I. Bromination of indomethacin // Mendeleev Communications. 2010. Vol. 20. No. 2. pp. 111-112.

RIS

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TY - JOUR

DO - 10.1016/j.mencom.2010.03.016

UR - https://mendcomm.colab.ws/publications/10.1016/j.mencom.2010.03.016

TI - Bromination of indomethacin

T2 - Mendeleev Communications

AU - Ivachtchenko, Alexandre Vasil'evich

AU - Yamanushkin, Pavel Mikhailovich

AU - Mitkin, Oleg Dmitrievich

AU - Kiselev, Oleg Ivanovich

PY - 2010

DA - 2010/03/05

PB - Mendeleev Communications

SP - 111-112

IS - 2

VL - 20

ER -

BibTex

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@article{2010_Ivachtchenko,

author = {Alexandre Vasil'evich Ivachtchenko and Pavel Mikhailovich Yamanushkin and Oleg Dmitrievich Mitkin and Oleg Ivanovich Kiselev},

title = {Bromination of indomethacin},

journal = {Mendeleev Communications},

year = {2010},

volume = {20},

publisher = {Mendeleev Communications},

month = {Mar},

url = {https://mendcomm.colab.ws/publications/10.1016/j.mencom.2010.03.016},

number = {2},

pages = {111--112},

doi = {10.1016/j.mencom.2010.03.016}

}

MLA

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Ivachtchenko, Alexandre Vasil'evich, et al. “Bromination of indomethacin.” Mendeleev Communications, vol. 20, no. 2, Mar. 2010, pp. 111-112. https://mendcomm.colab.ws/publications/10.1016/j.mencom.2010.03.016.

Abstract

Treatment of indomethacin with N-bromosuccinimide in AcOH results in bromination in aromatic positions 4 and 6, while the use of tetrachloromethane allows ultimate bromination at the C(2) Me group of the indole moiety to proceed.

References

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