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An efficient one-pot synthesis of 3-aryl-1,2,4-oxadiazol-5-amines under solvent-free conditions

Mehdi Adib 1
Mehdi Adib
, 
Sharareh Bagherzadeh 1
Sharareh Bagherzadeh
, 
Mohammad Mahdavi 1
Mohammad Mahdavi
, 
Hamid R Bijanzadeh 2
Hamid R Bijanzadeh
10.1016/j.mencom.2010.01.019
Published 2009-12-30
Communication , Volume 20, Issue 1, 50-51
10
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Adib M. et al. An efficient one-pot synthesis of 3-aryl-1,2,4-oxadiazol-5-amines under solvent-free conditions // Mendeleev Communications. 2009. Vol. 20. No. 1. pp. 50-51.
GOST all authors (up to 50) Copy
Adib M., Bagherzadeh S., Mahdavi M., Bijanzadeh H. R. An efficient one-pot synthesis of 3-aryl-1,2,4-oxadiazol-5-amines under solvent-free conditions // Mendeleev Communications. 2009. Vol. 20. No. 1. pp. 50-51.
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TY - JOUR
DO - 10.1016/j.mencom.2010.01.019
UR - https://mendcomm.colab.ws/publications/10.1016/j.mencom.2010.01.019
TI - An efficient one-pot synthesis of 3-aryl-1,2,4-oxadiazol-5-amines under solvent-free conditions
T2 - Mendeleev Communications
AU - Adib, Mehdi
AU - Bagherzadeh, Sharareh
AU - Mahdavi, Mohammad
AU - Bijanzadeh, Hamid R
PY - 2009
DA - 2009/12/30
PB - Mendeleev Communications
SP - 50-51
IS - 1
VL - 20
ER -
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@article{2009_Adib,
author = {Mehdi Adib and Sharareh Bagherzadeh and Mohammad Mahdavi and Hamid R Bijanzadeh},
title = {An efficient one-pot synthesis of 3-aryl-1,2,4-oxadiazol-5-amines under solvent-free conditions},
journal = {Mendeleev Communications},
year = {2009},
volume = {20},
publisher = {Mendeleev Communications},
month = {Dec},
url = {https://mendcomm.colab.ws/publications/10.1016/j.mencom.2010.01.019},
number = {1},
pages = {50--51},
doi = {10.1016/j.mencom.2010.01.019}
}
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MLA Copy
Adib, Mehdi, et al. “An efficient one-pot synthesis of 3-aryl-1,2,4-oxadiazol-5-amines under solvent-free conditions.” Mendeleev Communications, vol. 20, no. 1, Dec. 2009, pp. 50-51. https://mendcomm.colab.ws/publications/10.1016/j.mencom.2010.01.019.

Abstract

The in situ prepared amidoximes from the reaction between nitriles and hydroxylamine are condensed with carbodiimides in the presence of molecular sieves under solvent-free conditions to produce the title compounds in excellent yields.

References

1.
Solvent-free Organic Synthesis, 1st edn., ed. K. Tanaka, Wiley-VCH, Weinheim, 2004.
2.
Solvent-Free Organic Synthesis
Tanaka K., Toda F.
Chemical Reviews, 2000
3.
J. C. Jochims, in Comprehensive Heterocyclic Chemistry II, eds. A. R. Katritzky, C. W. Rees and E. F. V. Scriven, Pergamon Press, London, 1996, vol. 4, ch. 4, pp. 179–228 and references therein.
4.
K. Hemming, in Comprehensive Heterocyclic Chemistry III, eds. A. R. Katritzky, C. A. Ramsden, E. F. V. Scriven and R. J. K. Taylor,;1; Elsevier Science, Oxford, 2008, vol. 5, ch. 4, pp. 243–309 and references therein.
5.
Discovery of Potent and Selective SH2 Inhibitors of the Tyrosine Kinase ZAP-70
Vu C.B., Corpuz E.G., Merry T.J., Pradeepan S.G., Bartlett C., Bohacek R.S., Botfield M.C., Eyermann C.J., Lynch B.A., MacNeil I.A., Ram M.K., van Schravendijk M.R., Violette S., Sawyer T.K.
Journal of Medicinal Chemistry, 1999
6.
Novel 1, 2, 4-oxadiazoles as potent and selective histamine H3 receptor antagonists
Clitherow J.W., Beswick P., Irving W.J., Scopes D.I., Barnes J.C., Clapham J., Brown J.D., Evans D.J., Hayes A.G.
Bioorganic and Medicinal Chemistry Letters, 1996
7.
Effect of aminophylline, butalamine and imolamine on human isolated smooth muscle
Coupar I.M., Hedges A., Metcalfe H.L., Turner P.
Journal of Pharmacy and Pharmacology, 1969
8.
10.1016/j.mencom.2010.01.019_bib8
Dunsford
J. Natl. Cancer Inst., 1984
9.
Reaction of benzamide oxime with DCC
Kawashima E., Tabei K.
Journal of Heterocyclic Chemistry, 1986
10.
A Convenient Synthesis of 5-Amino-Substituted 1,2,4-Oxadiazole Derivatives via Reactions of Amidoximes with Carbodiimides
C. Fylaktakidou K., Ispikoudi M., E. Litinas K., C. Fylaktakidou K.
Heterocycles, 2008