Abstract
First 2-(phosphoryl)alkyl-substituted 1,6-naphthyridines have been synthesized by the Friedländer reaction between 4-amino-3-formylpyridine and phosphorus-containing ketones; their structures have been confirmed by 1H, 13C and 31P NMR spectroscopy and X-ray diffraction analysis.
References
1.
V. P. Litvinov, Khimiya naftiridinov (The Chemistry of Naphthyridines), Ekonomika, Moscow, 2008 (in Russian).
2.
Litvinov V.P.
Advances in Heterocyclic Chemistry,
2006
3.
Bodrin G.V., Lemport P.S., Matveev S.V., Petrovskii P.V., Nifant’ev E.E.
Mendeleev Communications,
2007
4.
Lemport P.S., Bodrin G.V., Pasechnik M.P., Matveeva A.G., Petrovskii P.V., Vologzhanina A.V., Nifant’ev E.E.
Russian Chemical Bulletin,
2007
5.
10.1016/j.mencom.2009.11.002_bib5
Cheng
Org. React.,
1983
6.
Dormer P.G., Eng K.K., Farr R.N., Humphrey G.R., McWilliams J.C., Reider P.J., Sager J.W., Volante R.P.
Journal of Organic Chemistry,
2002
7.
Turner J.A.
Journal of Organic Chemistry,
1983
8.
G. M. Sheldrick, SHELXTL v. 5.10, Structure Determination Software Suite, Bruker AXS, Madison, Wisconsin, USA.