Home / Publications / Three-component condensation of 2,4-diaminothiazoles with aldehydes and Meldrum's acid: synthesis of 7-aryl(alkyl)-substituted 6,7-dihydro-4H-thiazolo[4,5-b]pyridin-5-ones

Three-component condensation of 2,4-diaminothiazoles with aldehydes and Meldrum's acid: synthesis of 7-aryl(alkyl)-substituted 6,7-dihydro-4H-thiazolo[4,5-b]pyridin-5-ones

Arkady Anatol'evich Dudinov ¹

Arkady Anatol'evich Dudinov

Boris Valer'evich Lichitsky ¹

Boris Valer'evich Lichitsky

Andrey Nikolaevich Komogortsev ¹

Andrey Nikolaevich Komogortsev

Mikhail Mikhailovich Krayushkin ¹

Mikhail Mikhailovich Krayushkin

¹ N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russian Federation

10.1016/j.mencom.2009.03.011

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Published 2009-03-10

Communication , Volume 19, Issue 2, 87-88

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Dudinov A. A. et al. Three-component condensation of 2,4-diaminothiazoles with aldehydes and Meldrum's acid: synthesis of 7-aryl(alkyl)-substituted 6,7-dihydro-4H-thiazolo[4,5-b]pyridin-5-ones // Mendeleev Communications. 2009. Vol. 19. No. 2. pp. 87-88.

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Dudinov A. A., Lichitsky B. V., Komogortsev A. N., Krayushkin M. M. Three-component condensation of 2,4-diaminothiazoles with aldehydes and Meldrum's acid: synthesis of 7-aryl(alkyl)-substituted 6,7-dihydro-4H-thiazolo[4,5-b]pyridin-5-ones // Mendeleev Communications. 2009. Vol. 19. No. 2. pp. 87-88.

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TY - JOUR

DO - 10.1016/j.mencom.2009.03.011

UR - https://mendcomm.colab.ws/publications/10.1016/j.mencom.2009.03.011

TI - Three-component condensation of 2,4-diaminothiazoles with aldehydes and Meldrum's acid: synthesis of 7-aryl(alkyl)-substituted 6,7-dihydro-4H-thiazolo[4,5-b]pyridin-5-ones

T2 - Mendeleev Communications

AU - Dudinov, Arkady Anatol'evich

AU - Lichitsky, Boris Valer'evich

AU - Komogortsev, Andrey Nikolaevich

AU - Krayushkin, Mikhail Mikhailovich

PY - 2009

DA - 2009/03/10

PB - Mendeleev Communications

SP - 87-88

IS - 2

VL - 19

ER -

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@article{2009_Dudinov,

author = {Arkady Anatol'evich Dudinov and Boris Valer'evich Lichitsky and Andrey Nikolaevich Komogortsev and Mikhail Mikhailovich Krayushkin},

title = {Three-component condensation of 2,4-diaminothiazoles with aldehydes and Meldrum's acid: synthesis of 7-aryl(alkyl)-substituted 6,7-dihydro-4H-thiazolo[4,5-b]pyridin-5-ones},

journal = {Mendeleev Communications},

year = {2009},

volume = {19},

publisher = {Mendeleev Communications},

month = {Mar},

url = {https://mendcomm.colab.ws/publications/10.1016/j.mencom.2009.03.011},

number = {2},

pages = {87--88},

doi = {10.1016/j.mencom.2009.03.011}

}

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Dudinov, Arkady Anatol'evich, et al. “Three-component condensation of 2,4-diaminothiazoles with aldehydes and Meldrum's acid: synthesis of 7-aryl(alkyl)-substituted 6,7-dihydro-4H-thiazolo[4,5-b]pyridin-5-ones.” Mendeleev Communications, vol. 19, no. 2, Mar. 2009, pp. 87-88. https://mendcomm.colab.ws/publications/10.1016/j.mencom.2009.03.011.

Abstract

The new method of the synthesis of 6,7-dihydro-4H-thiazolo[4,5-b]pyridin-5-ones, based on decarboxylation of corresponding 2,4-diamino-5-thiazolecarboxylic acids has been elaborated; unstable derivatives of 2,4-diaminothiazole, generated in situ as a result of decarboxylation, react with aldehydes and Meldrum's acid forming target compounds.