Home / Publications / Synthesis of squalamine analogues on the basis of lupane triterpenoids

Synthesis of squalamine analogues on the basis of lupane triterpenoids

Gulnara Vladimirovna Giniyatullina 1
Gulnara Vladimirovna Giniyatullina
, 
Oxana Borisovna Flekhter 1
Oxana Borisovna Flekhter
, 
Genrikh Alexandrovich Tolstikov 1
Genrikh Alexandrovich Tolstikov
10.1016/j.mencom.2009.01.013
Published 2009-01-19
Communication , Volume 19, Issue 1, 32-33
6
Share
Cite this
GOST
 | 
Cite this
GOST Copy
Giniyatullina G. V., Flekhter O. B., Tolstikov G. A. Synthesis of squalamine analogues on the basis of lupane triterpenoids // Mendeleev Communications. 2009. Vol. 19. No. 1. pp. 32-33.
GOST all authors (up to 50) Copy
Giniyatullina G. V., Flekhter O. B., Tolstikov G. A. Synthesis of squalamine analogues on the basis of lupane triterpenoids // Mendeleev Communications. 2009. Vol. 19. No. 1. pp. 32-33.
RIS
 | 
Cite this
RIS Copy
TY - JOUR
DO - 10.1016/j.mencom.2009.01.013
UR - https://mendcomm.colab.ws/publications/10.1016/j.mencom.2009.01.013
TI - Synthesis of squalamine analogues on the basis of lupane triterpenoids
T2 - Mendeleev Communications
AU - Giniyatullina, Gulnara Vladimirovna
AU - Flekhter, Oxana Borisovna
AU - Tolstikov, Genrikh Alexandrovich
PY - 2009
DA - 2009/01/19
PB - Mendeleev Communications
SP - 32-33
IS - 1
VL - 19
ER -
BibTex
 | 
Cite this
BibTex (up to 50 authors) Copy
@article{2009_Giniyatullina,
author = {Gulnara Vladimirovna Giniyatullina and Oxana Borisovna Flekhter and Genrikh Alexandrovich Tolstikov},
title = {Synthesis of squalamine analogues on the basis of lupane triterpenoids},
journal = {Mendeleev Communications},
year = {2009},
volume = {19},
publisher = {Mendeleev Communications},
month = {Jan},
url = {https://mendcomm.colab.ws/publications/10.1016/j.mencom.2009.01.013},
number = {1},
pages = {32--33},
doi = {10.1016/j.mencom.2009.01.013}
}
MLA
Cite this
MLA Copy
Giniyatullina, Gulnara Vladimirovna, et al. “Synthesis of squalamine analogues on the basis of lupane triterpenoids.” Mendeleev Communications, vol. 19, no. 1, Jan. 2009, pp. 32-33. https://mendcomm.colab.ws/publications/10.1016/j.mencom.2009.01.013.

Keywords

betulin
polyamine
squalamine
steroids
synthesis
triterpenoids

Abstract

The first synthesis of a family of betulin-based triterpene–polyamine conjugates, which are structurally related to the potential antibiotic squalamine, is demonstrated.

References

1.
Squalamine: an aminosterol antibiotic from the shark.
Moore K.S., Wehrli S., Roder H., Rogers M., Forrest J.N., McCrimmon D., Zasloff M.
Proceedings of the National Academy of Sciences of the United States of America, 1993
2.
10.1016/j.mencom.2009.01.013_bib2
Savage
Exp. Opin. Invest. Drugs, 2000
3.
Steroidal Conjugates and Their Pharmacological Applications
Salunke D., Hazra B., Pore V.
Current Medicinal Chemistry, 2006
4.
10.1016/j.mencom.2009.01.013_bib4
Mancini
Chem., 2007
6.
Squalamine: a polyvalent drug of the future?
Brunel J., Salmi C., Loncle C., Vidal N., Letourneux Y.
Current Cancer Drug Targets, 2005
7.
A stereoselective synthesis of squalamine
Zhou X., Cai F., Zhou W.
Tetrahedron, 2002
8.
New 3-Aminosteroid Derivatives as a New Family of Topical Antibacterial Agents Active against Methicillin-Resistant Staphylococcus aureus (MRSA)
Salmi C., Loncle C., Vidal N., Laget M., Letourneux Y., Brunel J.
Letters in Drug Design and Discovery, 2008
9.
Pharmacological activities of natural triterpenoids and their therapeutic implications
Dzubak P., Hajduch M., Vydra D., Hustova A., Kvasnica M., Biedermann D., Markova L., Urban M., Sarek J.
Natural Product Reports, 2006
10.
10.1016/j.mencom.2009.01.013_bib10
Tolstikova
Bioorg. Khim., 2006
11.
Synthesis and anti-HIV activity of 3-alkylamido-3-deoxy-betulinic acid derivatives.
KASHIWADA Y., CHIYO J., IKESHIRO Y., NAGAO T., OKABE H., COSENTINO L.M., FOWKE K., MORRIS-NATSCHKE S.L., LEE K.
Chemical and Pharmaceutical Bulletin, 2011
12.
Synthesis and Antiviral Activity of Betulonic Acid Amides and Conjugates with Amino Acids
Flekhter O.B., Boreko E.I., Nigmatullina L.R., Tret'yakova E.V., Pavlova N.I., Baltina L.A., Nikolaeva S.N., Savinova O.V., Eremin V.F., Galin F.Z., Tolstikov G.A.
Russian Journal of Bioorganic Chemistry, 2004
13.
Synthesis of Polyamines, Their Derivatives, Analogues and Conjugates
Kuksa V., Buchan R., Kong Thoo Lin P.
Synthesis, 2000
14.
10.1016/j.mencom.2009.01.013_bib14
Rogoza
Khim. Interesakh Ustoich. Razvit., 2006
15.
Vystrčil A., Křeček V., Buděšínský M., Protiva J.
Collection of Czechoslovak Chemical Communications, 2010