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Ring-chain isomerism of ethyl 7-polyfluoroalkyl-7-hydroxy-4,7-dihydro[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxylates

Marina Valer'evna Pryadeina 1
Marina Valer'evna Pryadeina
, 
Yanina Valer'evna Burgart 1
Yanina Valer'evna Burgart
, 
Viktor Ivanovich Saloutin 1
Viktor Ivanovich Saloutin
, 
Oleg Nikolaevich Chupakhin 1
Oleg Nikolaevich Chupakhin
10.1016/j.mencom.2008.09.017
Published 2008-09-15
Communication , Volume 18, Issue 5, 276-277
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Pryadeina M. V. et al. Ring-chain isomerism of ethyl 7-polyfluoroalkyl-7-hydroxy-4,7-dihydro[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxylates // Mendeleev Communications. 2008. Vol. 18. No. 5. pp. 276-277.
GOST all authors (up to 50) Copy
Pryadeina M. V., Burgart Y. V., Saloutin V. I., Chupakhin O. N. Ring-chain isomerism of ethyl 7-polyfluoroalkyl-7-hydroxy-4,7-dihydro[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxylates // Mendeleev Communications. 2008. Vol. 18. No. 5. pp. 276-277.
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TY - JOUR
DO - 10.1016/j.mencom.2008.09.017
UR - https://mendcomm.colab.ws/publications/10.1016/j.mencom.2008.09.017
TI - Ring-chain isomerism of ethyl 7-polyfluoroalkyl-7-hydroxy-4,7-dihydro[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxylates
T2 - Mendeleev Communications
AU - Pryadeina, Marina Valer'evna
AU - Burgart, Yanina Valer'evna
AU - Saloutin, Viktor Ivanovich
AU - Chupakhin, Oleg Nikolaevich
PY - 2008
DA - 2008/09/15
PB - Mendeleev Communications
SP - 276-277
IS - 5
VL - 18
ER -
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@article{2008_Pryadeina,
author = {Marina Valer'evna Pryadeina and Yanina Valer'evna Burgart and Viktor Ivanovich Saloutin and Oleg Nikolaevich Chupakhin},
title = {Ring-chain isomerism of ethyl 7-polyfluoroalkyl-7-hydroxy-4,7-dihydro[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxylates},
journal = {Mendeleev Communications},
year = {2008},
volume = {18},
publisher = {Mendeleev Communications},
month = {Sep},
url = {https://mendcomm.colab.ws/publications/10.1016/j.mencom.2008.09.017},
number = {5},
pages = {276--277},
doi = {10.1016/j.mencom.2008.09.017}
}
MLA
Cite this
MLA Copy
Pryadeina, Marina Valer'evna, et al. “Ring-chain isomerism of ethyl 7-polyfluoroalkyl-7-hydroxy-4,7-dihydro[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxylates.” Mendeleev Communications, vol. 18, no. 5, Sep. 2008, pp. 276-277. https://mendcomm.colab.ws/publications/10.1016/j.mencom.2008.09.017.

Abstract

Cyclisation of ethyl 2-ethoxymethylidene-3-oxo-3-polyfluoroalkylpropionates with 3-amino-1H-[1,2,4]triazole gives ethyl 7-polyfluoroalkyl-7-hydroxy-4,7-dihydro[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxylates that are subject to ring–chain isomerisation in solution, depending on the solvent and the length of the polyfluoroalkyl substituent, to yield ethyl 3-polyfluoroalkyl-3-oxo-2-{([1,2,4]triazol-3-yl)aminomethylidene}propionates via heterocyclic ring opening at the C(7)–N(8) bond.

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